Product information
Background:This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
Product Overview
- Catalog No.
- WM1782
- SKU
- WM1782-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- CALCOCO2
- Reactivity
- Human
- Application
- WB,IF,ELISA
- MW(Calculated)
- 52kD
- MW(Observed)
- 55kD
- Host Species
- Mouse
- Isotype
- Mouse IgG1/Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein G
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PTR1440
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- CALCOCO2 NDP52
- Protein Name
- CALCOCO2
- Other Name
- Calcium-binding and coiled-coil domain-containing protein 2;Antigen nuclear dot 52 kDa protein;Nuclear domain 10 protein NDP52;Nuclear domain 10 protein 52;Nuclear dot protein 52;
- Organism-1
- Human
- Gene ID-1
- 10241
- SwissProt-1
- Q13137
- Organism-2
- Mouse
- Gene ID-2
- 76815
- SwissProt-2
- A2A6M5
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein . According to PubMed:7540613, localizes to nuclear dots. According to PubMed:9230084 and PubMed:12869526, it is not a nuclear dot-associated protein but localizes predominantly in the cytoplasm with a coarse-grained distribution preferentially close to the nucleus. .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)