Product information
Background:This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016],
Product Overview
- Catalog No.
- WM1780
- SKU
- WM1780-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- NR1H4
- Reactivity
- Human,Mouse
- Application
- WB,IF,IP,ELISA
- MW(Calculated)
- 56kD
- MW(Observed)
- 56kD
- Host Species
- Mouse
- Isotype
- IgG2a,kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein G
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PTR1431
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- NR1H4 BAR FXR HRR1 RIP14
- Protein Name
- Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Nuclear receptor subfamily 1 group H member 4) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 9971
- SwissProt-1
- Q96RI1
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q60641
- Organism-3
- Rat
- Gene ID-3
- --
- SwissProt-3
- Q62735
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus .; [Isoform 1]: Nucleus .; [Isoform 2]: Nucleus .; [Isoform 3]: Nucleus .; [Isoform 4]: Nucleus .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)