Product information
Background:tyrosinase(TYR) Homo sapiens The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008],
Product Overview
- Catalog No.
- WM1538
- SKU
- WM1538-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- Tyrosinase
- Reactivity
- Human,Mouse,
- Application
- IHC,WB,IF,ELISA
- MW(Calculated)
- 60kD
- MW(Observed)
- 50-80kD
- Host Species
- Mouse
- Isotype
- IgA,Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein G
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- ABT-TYR
- Immunogen
- Synthesized peptide derived from human Tyrosinase AA range: 250-350
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of Tyrosinase protein.
- Gene Name
- TYR
- Protein Name
- Tyrosinase
- Other Name
- ATN;CMM8;LB24 AB;LB24-AB;Monophenol monooxygenase;OCA1;OCA1A;OCAIA;Oculocutaneous albinism IA;SHEP3;SK29 AB;SK29-AB;Tumor rejection antigen AB;TYR;TYRO_HUMAN;tyrosinase;oculocutaneous albinism IA;Tyrosinase
- Organism-1
- Human
- Gene ID-1
- 7299
- SwissProt-1
- P14679
- Organism-2
- Mouse
- Gene ID-2
- 22173
- SwissProt-2
- P11344
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasmic
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)