Product information
Background:The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010],
Product Overview
- Catalog No.
- WM0686
- SKU
- WM0686-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- CD31
- Reactivity
- Human
- Application
- WB,IP
- MW(Calculated)
- --
- MW(Observed)
- 130kD
- Host Species
- Mouse
- Isotype
- --
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- --
- Immunogen
- Purified recombinant human CD31 protein fragments expressed in E.coli.
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of CD31 and does not cross-react with related proteins.
- Gene Name
- pecam1
- Protein Name
- --
- Other Name
- Adhesion molecule;CD31;CD31 antigen;CD31 EndoCAM;Endocam;FLJ34100;FLJ58394;GPIIA;GPIIA';PECA1;PECA1_HUMAN;Pecam 1;PECAM 1 CD31 EndoCAM;PECAM;PECAM-1;Pecam1;Platelet endothelial cell adhesion molecule;Platelet/endothelial cell adhesion molecule 1;Platelet/endothelial cell adhesion molecule.
- Organism-1
- Human
- Gene ID-1
- 18613
- SwissProt-1
- P16284
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q08481
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cell membrane ; Single-pass type I membrane protein . Cell surface expression on neutrophils is down-regulated upon fMLP or CXCL8/IL8-mediated stimulation. .; [Isoform Long]: Cell membrane ; Single-pass type I membrane protein . Membrane raft . Cell junction . Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells. .; [Isoform Delta15]: Cell junction . Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)