Product information
Background:thioredoxin reductase 2(TXNRD2) Homo sapiens This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013],
Product Overview
- Catalog No.
- WM0653
- SKU
- WM0653-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- TXNRD2
- Reactivity
- Human
- Application
- WB
- MW(Calculated)
- --
- MW(Observed)
- 56kD
- Host Species
- Mouse
- Isotype
- --
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- --
- Immunogen
- Purified recombinant human TXNRD2 protein fragments expressed in E.coli.
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of TXNRD2 and does not cross-react with related proteins.
- Gene Name
- txnrd2
- Protein Name
- Thioredoxin reductase 2 mitochondrial
- Other Name
- TXNRD2;KIAA1652;TRXR2;Thioredoxin reductase 2;mitochondrial;Selenoprotein Z;SelZ;TR-beta;Thioredoxin reductase TR3
- Organism-1
- Human
- Gene ID-1
- 10587
- SwissProt-1
- Q9NNW7
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q9JLT4
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Mitochondrion .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)