Product information
Background:This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011],
Product Overview
- Catalog No.
- WM0600
- SKU
- WM0600-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- PP5
- Reactivity
- Human
- Application
- WB
- MW(Calculated)
- --
- MW(Observed)
- 57kD
- Host Species
- Mouse
- Isotype
- --
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- --
- Immunogen
- Purified recombinant human PP5 protein fragments expressed in E.coli.
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of PP5 and does not cross-react with related protein
- Gene Name
- ppp5c
- Protein Name
- Serine/threonine-protein phosphatase 5
- Other Name
- FLJ36922;FLJ55954;OTTHUMP00000165834;PP-T;PP5;PPP5;PPP5_HUMAN;PPP5C;PPT;Protein phosphatase 5, catalytic subunit;Protein phosphatase T;Serine/threonine protein phosphatase 5;Serine/threonine-protein phosphatase 5.
- Organism-1
- Human
- Gene ID-1
- 5536
- SwissProt-1
- P53041
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q60676
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus . Cytoplasm . Cell membrane . Predominantly nuclear (PubMed:15383005). But also present in the cytoplasm (PubMed:15383005). Translocates from the cytoplasm to the plasma membrane in a RAC1-dependent manner (PubMed:19948726). .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)