Product information
Background:The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],
Product Overview
- Catalog No.
- WM0592
- SKU
- WM0592-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- Smad5
- Reactivity
- Human
- Application
- WB,ICC,FC
- MW(Calculated)
- --
- MW(Observed)
- 60kD
- Host Species
- Mouse
- Isotype
- --
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000;ICC 1:75;Flow Cyt 1:100
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- --
- Immunogen
- Purified recombinant human SMAD5 (C-terminus) protein fragments expressed in E.coli.
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of SMAD5 (C-terminus) and does not cross-react with related proteins.
- Gene Name
- smad5
- Protein Name
- --
- Other Name
- DKFZp781C1895;DKFZp781O1323;Dwfc;hSmad 5;hSmad5;JV5 1;JV5-1;MAD homolog 5;MAD mothers against decapentaplegic homolog 5;MAD, mothers against decapentaplegic homolog 5;MADH 5;MADH5;Mothers against decapentaplegic homolog 5;Mothers against DPP homolog 5;MusMLP;SMA and MAD related protein 5;SMAD 5;SMAD family member 5;SMAD mothers against DPP homolog 5;Smad5;Smad5;SMAD5_HUMAN.
- Organism-1
- Human
- Gene ID-1
- 4090
- SwissProt-1
- Q99717
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- P97454
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)