Product information
Background:This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009],
Product Overview
- Catalog No.
- WM0552
- SKU
- WM0552-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- KDM5C/Jarid1C/SMCX
- Reactivity
- Human
- Application
- WB,ICC
- MW(Calculated)
- --
- MW(Observed)
- 220kD
- Host Species
- Mouse
- Isotype
- --
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000;ICC 1:150
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- --
- Immunogen
- Purified recombinant human KDM5C / Jarid1C / SMCX protein fragments expressed in E.coli
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of KDM5C / Jarid1C / SMCX and does not corss-react with related proteins
- Gene Name
- kdm5c
- Protein Name
- Lysine-specific demethylase 5C
- Other Name
- KDM5C;DXS1272E;JARID1C;SMCX;XE169;Lysine-specific demethylase 5C;Histone demethylase JARID1C;Jumonji/ARID domain-containing protein 1C;Protein SmcX;Protein Xe169
- Organism-1
- Human
- Gene ID-1
- 8242
- SwissProt-1
- P41229
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- P41230
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)