Product information
Background:The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],
Product Overview
- Catalog No.
- WM0491
- SKU
- WM0491-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- Fyb
- Reactivity
- Human,Rat
- Application
- WB
- MW(Calculated)
- 85kD
- MW(Observed)
- --
- Host Species
- Mouse
- Isotype
- --
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000-1:2000;Not yet tested in other applications.
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- Affinity purification
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- --
- Immunogen
- Purified recombinant human Fyb protein fragments expressed in E.coli.
- Sequence
- --
- Specificity
- Fyb Monoclonal Antibody detects endogenous levels of Fyb protein.
- Gene Name
- FYB
- Protein Name
- FYN-binding protein
- Other Name
- FYB;SLAP130;FYN-binding protein;Adhesion and degranulation promoting adaptor protein;ADAP;FYB-120/130;p120/p130;FYN-T-binding protein;SLAP-130;SLP-76-associated phosphoprotein
- Organism-1
- Human
- Gene ID-1
- 2533
- SwissProt-1
- O15117
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- O35601
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasm . Nucleus . Cell junction . Colocalizes with TMEM47 at cell-cell contacts in podocytes. .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)