Product information
Background:This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
Product Overview
- Catalog No.
- WM0086
- SKU
- WM0086-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- Integrin β2
- Reactivity
- Human,Mouse
- Application
- IF,ELISA
- MW(Calculated)
- --
- MW(Observed)
- --
- Host Species
- Mouse
- Isotype
- --
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications;
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- Affinity purification
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- --
- Immunogen
- Purified recombinant fragment of CD18 expressed in E. Coli.
- Sequence
- --
- Specificity
- CD18 Monoclonal Antibody detects endogenous levels of CD18 protein.
- Gene Name
- ITGB2
- Protein Name
- Integrin beta-2
- Other Name
- ITGB2;CD18;MFI7;Integrin beta-2;Cell surface adhesion glycoproteins LFA-1/CR3/p150;95 subunit beta;Complement receptor C3 subunit beta;CD antigen CD18
- Organism-1
- Human
- Gene ID-1
- 3689
- SwissProt-1
- P05107
- Organism-2
- Mouse
- Gene ID-2
- 16414
- SwissProt-2
- P11835
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)