Product information
Background:The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Product Overview
- Catalog No.
- WM0009
- SKU
- WM0009-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- AAT
- Reactivity
- Human,Mouse
- Application
- WB,ELISA
- MW(Calculated)
- 47kD
- MW(Observed)
- --
- Host Species
- Mouse
- Isotype
- --
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- Affinity purification
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- --
- Immunogen
- Purified recombinant fragment of human AAT expressed in E. Coli.
- Sequence
- --
- Specificity
- AAT Monoclonal Antibody detects endogenous levels of AAT protein.
- Gene Name
- SERPINA1
- Protein Name
- Alpha-1-antitrypsin
- Other Name
- SERPINA1;AAT;PI;Alpha-1-antitrypsin;Alpha-1 protease inhibitor;Alpha-1-antiproteinase;Serpin A1
- Organism-1
- Human
- Gene ID-1
- 5265
- SwissProt-1
- P01009
- Organism-2
- --
- Gene ID-2
- --
- SwissProt-2
- --
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Secreted. Endoplasmic reticulum. The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum.; [Short peptide from AAT]: Secreted, extracellular space, extracellular matrix.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)