U-Blot® Mouse ROS1 Recombinant Antibody

Name: U-Blot® Mouse ROS1 Recombinant Antibody
SKU: WE2509
Availability: InStock

$9,999.00

Size:50ug

SKU: WE2509-50

Catalog No.: WE2509

Specification: 50ug/100ug

Stock: In stock

U-Blot® Mouse ROS1 Recombinant Antibody Learn more

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U-Blot® Mouse ROS1 Recombinant Antibody

Product Overview

Catalog No.: WE2509
SKU: WE2509-50
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: EC:2.7.10.1, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, Proto-oncogene tyrosine-protein kinase ROS, Receptor tyrosine kinase c-ros oncogene 1, Ros, Ros-1, Ros1, c-Ros receptor tyrosine kinase
Reactivity: Mouse
Applications: ELISA
Host Species: Human
Isotype: IgG1, kappa
Conjugate/Modification: --
Recommended Dilution Ratio: Application Dilution ELISA 1:2000-1:20000
Composition: 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Clonality: Monoclonal
Clone Number: VFA2777
Immunogen: --
Alias: --
Species: --
Gene ID-1: Q78DX7
Uniprot: --
Background: Proto-oncogene tyrosine-protein kinase ROS (ROS1) is a ~261 kDa protein. Receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. NELL2 is an endogenous ligand for ROS1. Upon endogenous stimulation by NELL2, ROS1 activates the intracellular signaling pathway and triggers epididymal epithelial differentiation and subsequent sperm maturation. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. 1. Kiyozumi, D. et al. (2020) Science (New York, N.Y.) 368, 1132-1135. PMID: 32499443
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.