U-Blot® galactose-deficient IgA1 Recombinant Antibody (KM55)

Name: U-Blot® galactose-deficient IgA1 Recombinant Antibody (KM55)
SKU: WE2460
Availability: InStock

$9,999.00

Size:50ug

SKU: WE2460-50

Catalog No.: WE2460

Specification: 50ug/100ug

Stock: In stock

U-Blot® galactose-deficient IgA1 Recombinant Antibody (KM55) Learn more

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U-Blot® galactose-deficient IgA1 Recombinant Antibody (KM55)

Product Overview

Catalog No.: WE2460
SKU: WE2460-50
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: galactose-deficient IgA1, Gd-IgA1, IGHA1, Ig alpha-1 chain C region, Ig alpha-1 chain C region BUR, Ig alpha-1 chain C region TRO, Immunoglobulin heavy constant alpha 1
Reactivity: Human
Applications: ELISA, IF, IHC
Host Species: Rat
Isotype: IgG2b, kappa
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Clonality: Monoclonal
Clone Number: KM55
Immunogen: --
Alias: --
Species: --
Gene ID-1: P01876
Uniprot: --
Background: Immunoglobulin heavy constant alpha 1 (Gd-IgA1) is a ~42 kDa protein. Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. 1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414 3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170 4. Kerr, MA. (1990) The Biochemical journal 271, 285-96. PMID: 2241915
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.