- PackSize
- 50ug/100ug
- Target
- EC:3.4.21.59, TPS1, TPS2, TPSAB1, TPSB1, Tryptase I, Tryptase alpha-1, Tryptase alpha/beta-1, Tryptase-1
- Reactivity
- Human
- Applications
- ELISA
- Host Species
- Human
- Isotype
- IgG1, kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS pH 7.4
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Clonality
- Monoclonal
- Clone Number
- E104.v2
- Immunogen
- --
- Alias
- --
- Species
- --
- Gene ID-1
- Q15661
- Uniprot
- --
- Background
- Tryptase alpha/beta-1 (β-tryptase/TPSAB1) is a ~30 kDa protein. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.
1. Jackson, NE. et al. (2008) The Journal of biological chemistry 283, 34178-87.
PMID: 18854315
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --