- PackSize
- 50ug/100ug
- Target
- clfAClumping factor A
- Reactivity
- Staphylococcus aureus
- Applications
- ELISA, Functional assay, Research in vivo
- Host Species
- Humanized
- Isotype
- IgG1-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- clfAClumping factor A
- Species
- --
- Gene ID-1
- Q53653, Q2G015, Q5HHM8
- Uniprot
- --
- Background
- Tefibazumab is a humanized IgG1κ monoclonal antibody that binds to the surface-expressed adhesion protein clumping factor A. Tefibazumab can be used for the research of serious Staphylococcus aureus infections.<br>• Diabetic retinopathy., PMID:22455417<br/>• Novel Target for Limiting VEGF-A (Vascular Endothelial Growth Factor A)-Induced Vascular Permeability., PMID:36004641<br/>• Vascular endothelial growth factor-A as a promising therapeutic target for the management of psoriasis., PMID:32654325<br/>• Interleukin-37, vascular endothelial growth factor A, and transforming growth factor-β1: promising biomarkers in primary immune thrombocytopenia., PMID:35815383<br/>• [Research progress of vascular endothelial growth factor-A and its isoforms in kidney disease]., PMID:35199126<br/>• Life and Death of Podocytes: Not Only a Matter of Vascular Endothelial Growth Factor., PMID:26930245<br/>• Preface., PMID:30612609<br/>• Monoclonal antibodies neutralizing alpha-hemolysin, bicomponent leukocidins, and clumping factor A protected against <i>Staphylococcus aureus</i>-induced acute circulatory failure in a mechanically ventilated rabbit model of hyperdynamic septic shock., PMID:37781371<br/>• Diabetic retinopathy., PMID:22784133<br/>• Diabetic retinopathy., PMID:22784134<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --