- PackSize
- 50ug/100ug
- Target
- CD3E
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Humanized
- Isotype
- scFv-TCR
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 9mM Citric acid monohydrate, 41mM Na2HPO4, 1% Mannitol, 5% Trehalose, 0.02% Tween 20, 2mM DTT, pH 6.5.
- Purification Process
- Purified by Nickel column.
- Purity
- >95% as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- CD3E, gp100 peptide-HLA Complex, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, T-cell surface glycoprotein CD3 epsilon chain
- Species
- --
- Gene ID-1
- P07766
- Uniprot
- --
- Background
- Dafsolimab (SPV-T3a) is an IgG2a murine monoclonal antibody (anti-CD3). Dafsolimab can induce cell death through modulation and activation of the CD3/T cell receptor complex. Dafsolimab can be used for the research of graft-versus-host disease (GVHD).<br>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --