- PackSize
- 50ug/100ug
- Target
- DPEP3
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Humanized
- Isotype
- IgG1-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- DPEP3, Dipeptidase 3
- Species
- --
- Gene ID-1
- Q9H4B8
- Uniprot
- --
- Background
- Technetium (99mTc) pintumomab (INN) is a mouse monoclonal antibody for the imaging of adenocarcinoma. It is labelled with the radioisotope technetium-99m.<br>• ADC: a deadly killer of platinum resistant ovarian cancer., PMID:39367438<br/>• A mini-overview of antibody-drug conjugates in platinum-resistant ovarian cancer: A preclinical and clinical perspective., PMID:39922351<br/>• Molecular characterization and expression of dipeptidase 3, a testis-specific membrane-bound dipeptidase: complex formation with TEX101, a germ-cell-specific antigen in the mouse testis., PMID:21724266<br/>• Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity., PMID:32325220<br/>• Tamrintamab pamozirine (SC-003) in patients with platinum-resistant/refractory ovarian cancer: Findings of a phase 1 study., PMID:32513564<br/>• The testis-specifically expressed Dpep3 is not essential for male fertility in mice., PMID:31212048<br/>• Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies., PMID:30097533<br/>• Effects of varicocele and microsurgical varicocelectomy on the metabolites in semen., PMID:35338186<br/>• Identification of two additional members of the membrane-bound dipeptidase family., PMID:12738806<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --