- PackSize
- 50ug/100ug
- Target
- Vascular endothelial growth factor C
- Reactivity
- Human
- Applications
- ELISA, Functional assay, Research in vivo
- Host Species
- Mammalian Cells
- Isotype
- Vascular Endothelial Growth Factor Receptor 3 fusion protein with IgG1 Fc Fragment.
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- Vascular endothelial growth factor C, VEGFC, Flt4-L, VEGF-C, Vascular endothelial growth factor-related protein, VRP, Flt4 ligand, Vascular endothelial growth factor D, VEGF-D, FIGF, VEGFD, c-Fos-induced growth factor
- Species
- --
- Gene ID-1
- P49767 & O43915
- Uniprot
- --
- Background
- Sozinibercept (OPT 302; VGX-300) is a soluble form of VEGFR-3, potently inhibits the activity of VEGF-C/D, which are the proangiogenic factors, inhibiting angiogenesis and vascular leakage. Sozinibercept also inhibits diabetic retinal edema in rats.<br>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --