U-Blot® Research Grade Sirtratumab

Name: U-Blot® Research Grade Sirtratumab
SKU: WA3543
Availability: InStock

$9,999.00

Size:50ug

SKU: WA3543-50

Catalog No.: WA3543

Specification: 50ug/100ug

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product details Specifications Q & A Education

Product details, specifications, documents, and related products are available from the catalog record.

Product Overview

Catalog No.: WA3543
SKU: WA3543-50
Category: Biosimilar Antibodies
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: SLITRK6
Reactivity: Human
Applications: ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host Species: Human
Isotype: IgG2-kappa
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 30 mM Histidine, pH5.8, 10% sucrose, 0.02% Tween80
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% purity as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Clonality: Monoclonal
Clone Number: --
Immunogen: Mammalian Cells
Alias: SLITRK6, SLIT and NTRK-like protein 6
Species: --
Gene ID-1: Q9H5Y7
Uniprot: --
Background: Sirtratumab is a human Igγ2 monoclonal antibody against SLIT and NTRK-like family 6 (Slitrk6). Sirtratumab can be used in research of cancer. • SLITRK6 promotes the progression of lung adenocarcinoma by regulating PI3K/AKT/mTOR signaling and Warburg effect., PMID:37219677 • SLITRK6 mutations cause myopia and deafness in humans and mice., PMID:23543054 • Differential expression of SLITRK6 gene as a potential therapeutic target for urothelial carcinoma in particular upper tract cancer., PMID:37353040 • The role of SLITRK6 in the pathogenesis of Tourette syndrome: From the conclusion of a family-based study in the Chinese Han population., PMID:32037697 • A novel mutation in SLITRK6 causes deafness and myopia in a Moroccan family., PMID:29551497 • A homozygous SLITRK6 nonsense mutation is associated with progressive auditory neuropathy in humans., PMID:23946138 • Transcriptomic Profiling Discloses Molecular and Cellular Events Related to Neuronal Differentiation in SH-SY5Y Neuroblastoma Cells., PMID:27422411 • Human cytomegalovirus downregulates SLITRK6 expression through IE2., PMID:27530937 • Born This Way: Using Intrinsic Disorder to Map the Connections between SLITRKs, TSHR, and Male Sexual Orientation., PMID:30156382
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.