U-Blot® Research Grade Sifarobocept

Name: U-Blot® Research Grade Sifarobocept
SKU: WA3530
Availability: InStock

$9,999.00

Size:50ug

SKU: WA3530-50

Catalog No.: WA3530

Specification: 50ug/100ug

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product details Specifications Q & A Education

Product details, specifications, documents, and related products are available from the catalog record.

Product Overview

Catalog No.: WA3530
SKU: WA3530-50
Category: Biosimilar Antibodies
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: Roundabout homolog 2
Reactivity: Human
Applications: ELISA, Functional assay, Research in vivo
Host Species: Mammalian Cells
Isotype: Human ROBO2 fragment (1-203), fused to human IgG1 Fc fragment
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 0.01M PBS, pH 7.4.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% purity as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Clonality: --
Clone Number: --
Immunogen: Mammalian Cells
Alias: Roundabout homolog 2, KIAA1568, ROBO2
Species: --
Gene ID-1: Q9HCK4
Uniprot: --
Background: Sifarobocept is a recombinant fusion protein comprising an roundabout guidance receptor 2 (ROBO2) fused to a human IgG1 Fc. • Loss of Roundabout Guidance Receptor 2 (Robo2) in Podocytes Protects Adult Mice from Glomerular Injury by Maintaining Podocyte Foot Process Structure., PMID:32220420 • Conformational Change of the Hairpin-like-structured Robo2 Ectodomain Allows NELL1/2 Binding., PMID:35940226 • Robo2 contains a cryptic binding site for neural EGFL-like (NELL) protein 1/2., PMID:30700556 • Function of Slit/Robo signaling in breast cancer., PMID:26542734 • Genome-Wide Association Study Identifies ROBO2 as a Novel Susceptibility Gene for Anthracycline-Related Cardiomyopathy in Childhood Cancer Survivors., PMID:36508697 • Down-regulation of ROBO2 expression in prostate cancers., PMID:24272677 • Structural Principles in Robo Activation and Auto-inhibition., PMID:30853216 • ROBO2 hampers malignant biological behavior and predicts a better prognosis in pancreatic adenocarcinoma., PMID:34148491 • An ancient founder mutation located between ROBO1 and ROBO2 is responsible for increased microtia risk in Amerindigenous populations., PMID:35584116 • Alterations of ROBO1/DUTT1 and ROBO2 loci in early dysplastic lesions of head and neck: clinical and prognostic implications., PMID:19104841
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.