U-Blot® Research Grade Sevirumab

Name: U-Blot® Research Grade Sevirumab
SKU: WA3525
Availability: InStock

$9,999.00

Size:50ug

SKU: WA3525-50

Catalog No.: WA3525

Specification: 50ug/100ug

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product details Specifications Q & A Education

Product details, specifications, documents, and related products are available from the catalog record.

Product Overview

Catalog No.: WA3525
SKU: WA3525-50
Category: Biosimilar Antibodies
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: Envelope glycoprotein H
Reactivity: Human cytomegalovirus (HCMV/HHV-5)
Applications: ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host Species: Human
Isotype: IgG1, kappa
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 0.01M PBS, pH 7.4.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% purity as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Clonality: Monoclonal
Clone Number: --
Immunogen: Mammalian Cells
Alias: Envelope glycoprotein H, gH, gH, UL75
Species: --
Gene ID-1: P12824
Uniprot: --
Background: Sevirumab (MSL-109) is a human IgG1 neutralizing monoclonal antibody against cytomegalovirus (CMV). Sevirumab recognizes CMV gH complexes and inhibits CMV replication with an EC50 of 0.3 μg/mL. • Characterization of the human cytomegalovirus UL75 (glycoprotein H) late gene promoter., PMID:12490392 • Viral shedding, and distribution of cytomegalovirus glycoprotein H (UL75), glycoprotein B (UL55), and glycoprotein N (UL73) genotypes in congenital cytomegalovirus infection., PMID:32086150 • Human cytomegalovirus envelope glycoprotein B, H, and N polymorphisms among infants of Shanghai area in China., PMID:32567060 • Cytomegalovirus glycoprotein H genotype distribution and the relationship with hearing loss in children., PMID:24615599 • The human cytomegalovirus UL55 (gB) and UL75 (gH) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infection., PMID:9188570 • Cytomegalovirus Genetic Diversity Following Primary Infection., PMID:31593588 • Glycoprotein H of human cytomegalovirus (HCMV) forms a stable complex with the HCMV UL115 gene product., PMID:1328481 • Distribution of the CMV glycoprotein gH/gL/gO and gH/gL/pUL128/pUL130/pUL131A complex variants and associated clinical manifestations in infants infected congenitally or postnatally., PMID:31705022 • Characterization of a novel third member of the human cytomegalovirus glycoprotein H-glycoprotein L complex., PMID:9188610 • Expression and reconstitution of the gH/gL/gO complex of human cytomegalovirus., PMID:12361760
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.