- PackSize
- 50ug/100ug
- Target
- Leucine-rich repeat protein induced by beta-amyloid homolog
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Humanized
- Isotype
- IgG1-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- Leucine-rich repeat protein induced by beta-amyloid homolog, LRRC15, Leucine-rich repeat-containing protein 15, LIB, hLib
- Species
- --
- Gene ID-1
- Q8TF66
- Uniprot
- --
- Background
- Samrotamab is a humanized IgG1-κ chimeric antibody targeting LRRC15.<br>• A novel member of the leucine-rich repeat superfamily induced in rat astrocytes by beta-amyloid., PMID:11785964<br/>• Mediators of inflammation and regeneration., PMID:21677081<br/>• Lib, transcriptionally induced in senile plaque-associated astrocytes, promotes glial migration through extracellular matrix., PMID:16098915<br/>• High lib mRNA expression in breast carcinomas., PMID:15368894<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --