- PackSize
- 50ug/100ug
- Target
- CD39
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Human
- Isotype
- IgG4-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- Ecto-ATP diphosphohydrolase 1, NTPDase 1, ENTPD1, Ecto-ATPase 1, Ecto-apyrase, Ecto-ATPDase 1, Ectonucleoside triphosphate diphosphohydrolase 1, CD39, Lymphoid cell activation antigen
- Species
- --
- Gene ID-1
- P49961
- Uniprot
- --
- Background
- Eurestobart is a humanized IgG1κ antibody targeting ENTPDase.<br>• CD39 and CD73 in immunity and inflammation., PMID:23601906<br/>• Ectonucleoside triphosphate diphosphohydrolase-1 (CD39) impacts TGF-β1 responses: insights into cardiac fibrosis and function following myocardial infarction., PMID:36240436<br/>• Favorable function of Ectonucleoside triphosphate diphosphohydrolase 1 high expression in thyroid carcinoma., PMID:34465393<br/>• Ectonucleoside triphosphate diphosphohydrolase-1 (E-NTPDase1/CD39) as a new prognostic marker in chronic lymphocytic leukemia., PMID:24684231<br/>• Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells., PMID:37399271<br/>• ATP signaling and NTPDase in Systemic Lupus Erythematosus (SLE)., PMID:30803848<br/>• Heterologous cell-cell interactions: thromboregulation, cerebroprotection and cardioprotection by CD39 (NTPDase-1)., PMID:14675084<br/>• Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection., PMID:15852226<br/>• CD39/ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury., PMID:17909107<br/>• Ectonucleoside triphosphate diphosphohydrolase 1 and 5'-nucleotidase ecto gene polymorphisms and acute cellular rejection after liver transplantation., PMID:32248630<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --