- PackSize
- 50ug/100ug
- Target
- ROR2
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Humanized
- Isotype
- IgG1-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- ROR2, Neurotrophic tyrosine kinase, receptor-related 2, NTRKR2, Tyrosine-protein kinase transmembrane receptor ROR2
- Species
- --
- Gene ID-1
- Q01974
- Uniprot
- --
- Background
- Ozuriftamab is a naked human IgG1 kappa antibody of receptor tyrosine kinase-like orphan receptor 2 ROR2, can be used to synthesis ADC.<br>• A proteogenomic portrait of lung squamous cell carcinoma., PMID:34358469<br/>• WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth., PMID:36622276<br/>• ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma., PMID:38975886<br/>• Robinow syndrome., PMID:12011143<br/>• Ror2 as a therapeutic target in cancer., PMID:25614331<br/>• Prognostic value of receptor tyrosine kinase-like orphan receptor (ROR) family in cancer: A meta-analysis., PMID:31174180<br/>• Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis., PMID:32951408<br/>• The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis., PMID:23233346<br/>• Heterogeneous expression and role of receptor tyrosine kinase-like orphan receptor 2 (ROR2) in small cell lung cancer., PMID:36463543<br/>• Purification and characterization of the extracellular region of human receptor tyrosine kinase like orphan receptor 2 (ROR2)., PMID:30826310<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --