U-Blot® Research Grade Narnatumab

Name: U-Blot® Research Grade Narnatumab
SKU: WA3207
Availability: InStock

$9,999.00

Size:50ug

SKU: WA3207-50

Catalog No.: WA3207

Specification: 50ug/100ug

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product details Specifications Q & A Education

Product details, specifications, documents, and related products are available from the catalog record.

Product Overview

Catalog No.: WA3207
SKU: WA3207-50
Category: Biosimilar Antibodies
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: CD136
Reactivity: Human
Applications: ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host Species: Human
Isotype: IgG1-kappa
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 0.01M PBS, pH 7.4.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% purity as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Clonality: Monoclonal
Clone Number: --
Immunogen: Mammalian Cells
Alias: CD136, Macrophage-stimulating protein receptor, PTK8, MST1R, p185-Ron, RON, CDw136, MSP receptor, Protein-tyrosine kinase 8
Species: --
Gene ID-1: Q04912
Uniprot: --
Background: Narnatumab (IMC-RON8) is a neutralizing human monoclonal antibody that blocks RON binding to its ligand, macrophage-stimulating protein (MSP), with a Kd of 32 pM. Narnatumab can be used for the research of cancer. • Macrophage-stimulating protein and RON receptor tyrosine kinase: potential regulators of macrophage inflammatory activities., PMID:12472665 • Macrophage stimulating protein., PMID:10549357 • MSP-RON Pathway: Potential Regulator of Inflammation and Innate Immunity., PMID:33117355 • An Introduction and Overview of RON Receptor Tyrosine Kinase Signaling., PMID:36833444 • Oncogenic and invasive potentials of human macrophage-stimulating protein receptor, the RON receptor tyrosine kinase., PMID:12807733 • Roles of macrophage stimulating protein and tyrosine kinase receptor RON in smoke-induced airway inflammation of rats., PMID:26464622 • Kinases involved in MSP/RON signaling., PMID:10080538 • Role of macrophage-stimulating protein and its receptor, RON tyrosine kinase, in ciliary motility., PMID:9045873 • MSP-RON signalling in cancer: pathogenesis and therapeutic potential., PMID:23792360 • The ron receptor tyrosine kinase: a key regulator of inflammation and cancer progression., PMID:24266348
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.