- PackSize
- 50ug/100ug
- Target
- HA/Hemagglutinin
- Reactivity
- Influenza B virus
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Human
- Isotype
- IgG1, kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- HA/Hemagglutinin
- Species
- --
- Gene ID-1
- P03461
- Uniprot
- --
- Background
- Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody.<br>• SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity., PMID:31913745<br/>• KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity., PMID:35266843<br/>• Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression., PMID:35253629<br/>• <i>Streptococcus pneumoniae</i> extracellular vesicles aggravate alveolar epithelial barrier disruption via autophagic degradation of OCLN (occludin)., PMID:38497494<br/>• Engineered Macrophage Membrane-Coated S100A9-siRNA for Ameliorating Myocardial Ischemia-Reperfusion Injury., PMID:39264262<br/>• Phosphorylation of ATG18a by BAK1 suppresses autophagy and attenuates plant resistance against necrotrophic pathogens., PMID:32804012<br/>• TRIM22 facilitates autophagosome-lysosome fusion by mediating the association of GABARAPs and PLEKHM1., PMID:38009729<br/>• A/(H1N1) pdm09 NS1 promotes viral replication by enhancing autophagy through hijacking the IAV negative regulatory factor LRPPRC., PMID:36300799<br/>• Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway., PMID:35130104<br/>• Phosphorylation of EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha) is indispensable for nuclear translocation of TFEB and TFE3 during ER stress., PMID:36719671<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --