U-Blot® Research Grade Ladiratuzumab

Name: U-Blot® Research Grade Ladiratuzumab
SKU: WA3035
Availability: InStock

$9,999.00

Size:50ug

SKU: WA3035-50

Catalog No.: WA3035

Specification: 50ug/100ug

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product details Specifications Q & A Education

Product details, specifications, documents, and related products are available from the catalog record.

Product Overview

Catalog No.: WA3035
SKU: WA3035-50
Category: Biosimilar Antibodies
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: SLC39A6
Reactivity: Human
Applications: ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host Species: Humanized
Isotype: IgG1-kappa
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 0.01M PBS, pH 7.4.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% purity as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Clonality: Monoclonal
Clone Number: --
Immunogen: Mammalian Cells
Alias: SLC39A6, LIV1, Zrt- and Irt-like protein 6, Zinc transporter ZIP6, ZIP-6, Estrogen-regulated protein LIV-1, Solute carrier family 39 member 6, ZIP6
Species: --
Gene ID-1: Q13433
Uniprot: --
Background: Ladiratuzumab (hLIV22) is an anti-LIV-1/ZIP6 humanized monoclonal antibody. Ladiratuzumab, conjugated with the microtubule disrupting agent, MMAE to compose SGN-LIV1A, an antibody-drug conjugate (ADC). Ladiratuzumab can be used for research of breast cancer. • Zinc and cancer: implications for LIV-1 in breast cancer., PMID:22852056 • Recombinant Expression of Zinc Transporter SLC39A6 and Its Functional Antibody Production., PMID:31009334 • Zip6 (LIV-1) regulates zinc uptake in neuroblastoma cells under resting but not depolarizing conditions., PMID:18272141 • A mechanism for epithelial-mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3)., PMID:23919497 • Concordant correlation of LIV-1 and E-cadherin expression in human breast cancer cell MCF-7., PMID:18330719 • Zip6-attenuation promotes epithelial-to-mesenchymal transition in ductal breast tumor (T47D) cells., PMID:19852955 • Microarray analyses of oral punch biopsies from acute myeloid leukemia (AML) patients treated with chemotherapy., PMID:21862359
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.