- PackSize
- 50ug/100ug
- Target
- CD278
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Humanized
- Isotype
- half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- CD278, ICOS, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, AILIM, Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
- Species
- --
- Gene ID-1
- Q9Y6W8 & Q15116
- Uniprot
- --
- Background
- Izuralimab is a bispecific IgG1 antibody targeting inducible T-cell costimulator (ICOS/CD278) and PD-1.<br>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --