U-Blot® Research Grade Iluzanebart

Name: U-Blot® Research Grade Iluzanebart
SKU: WA2965
Availability: InStock

$9,999.00

Size:50ug

SKU: WA2965-50

Catalog No.: WA2965

Specification: 50ug/100ug

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product details Specifications Q & A Education

Product details, specifications, documents, and related products are available from the catalog record.

Product Overview

Catalog No.: WA2965
SKU: WA2965-50
Category: Biosimilar Antibodies
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: Triggering receptor expressed on myeloid cells 2
Reactivity: Human
Applications: ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host Species: Human
Isotype: IgG1-kappa
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 0.01M PBS, pH 7.4.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% purity as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Clonality: Monoclonal
Clone Number: --
Immunogen: Mammalian Cells
Alias: Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, TREM-2, TREM2
Species: --
Gene ID-1: Q9NZC2
Uniprot: --
Background: Iluzanebart is a human IgG1κ antibody targeting TREM2, a triggering receptor expressed on myeloid cells. • Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma., PMID:38237157 • TREM2, microglia, and Alzheimer's disease., PMID:33516818 • Distinct roles of TREM2 in central nervous system cancers and peripheral cancers., PMID:38788719 • TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration., PMID:37442133 • TREM2, Microglia, and Neurodegenerative Diseases., PMID:28442216 • Microglia and TREM2., PMID:38821351 • TREM2 dependent and independent functions of microglia in Alzheimer's disease., PMID:36564824 • TREM2: A new player in the tumor microenvironment., PMID:36989543 • TREM2 sustains macrophage-hepatocyte metabolic coordination in nonalcoholic fatty liver disease and sepsis., PMID:33586673 • How neuroinflammation contributes to neurodegeneration., PMID:27540165
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.