- PackSize
- 50ug/100ug
- Target
- Dabigatran Etexilate Mesylate
- Reactivity
- General
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Humanized
- Isotype
- Fab-G1-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- Dabigatran Etexilate Mesylate
- Species
- --
- Gene ID-1
- 211915-06-9
- Uniprot
- --
- Background
- Idarucizumab is a humanized monoclonal antibody fragment. Idarucizumab is first reversal agent for a direct oral anticoagulant (DOAC). Idarucizumab can specifically neutralize the effects of the oral direct thrombin inhibitor in order to restore hemostasis.<br>• Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial., PMID:33290737<br/>• Dabigatran Etexilate: A Review in Pediatric Venous Thromboembolism., PMID:35699915<br/>• The polymorph landscape of dabigatran etexilate mesylate: Taking the challenge to bring a metastable polymorph to market., PMID:37044200<br/>• Dose tailoring of dabigatran etexilate: obvious or excessive?, PMID:25994994<br/>• A Pharmacokinetic Evaluation of Dabigatran Etexilate, Total Dabigatran, and Unconjugated Dabigatran Following the Administration of Dabigatran Etexilate Mesylate Capsules in Healthy Male and Female Subjects., PMID:31652461<br/>• Idarucizumab for Dabigatran Reversal - Full Cohort Analysis., PMID:28693366<br/>• Dabigatran Etexilate: A Review in Nonvalvular Atrial Fibrillation., PMID:28185082<br/>• Direct oral anticoagulants: evidence and unresolved issues., PMID:33248499<br/>• Transfer of dabigatran and dabigatran etexilate mesylate across the dually perfused human placenta., PMID:24807346<br/>• The discovery of dabigatran etexilate for the treatment of venous thrombosis., PMID:27159158<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --