U-Blot® Research Grade Enokizumab

Name: U-Blot® Research Grade Enokizumab
SKU: WA2796
Availability: InStock

$9,999.00

Size:50ug

SKU: WA2796-50

Catalog No.: WA2796

Specification: 50ug/100ug

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product details Specifications Q & A Education

Product details, specifications, documents, and related products are available from the catalog record.

Product Overview

Catalog No.: WA2796
SKU: WA2796-50
Category: Biosimilar Antibodies
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: --
Reactivity: Human
Applications: ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host Species: Humanized
Isotype: IgG1-kappa
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 0.01M PBS, pH 7.4.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clonality: Monoclonal
Clone Number: --
Immunogen: Mammalian Cells
Alias: T-cell growth factor P40, Cytokine P40, IL9, Interleukin-9, IL-9
Species: --
Gene ID-1: P15248
Uniprot: --
Background: Enokizumab (MEDI-528) is a monoclonal antibody targeting to interleukin (IL)-9. IL-9 regulates the development of airway inflammation, mucus production, airway hyperresponsiveness, and airway fibrosis largely by increasing mast cell numbers and activity in the airways. • IL-9 secreted by leukemia stem cells induces Th1-skewed CD4+ T cells, which promote their expansion., PMID:38941612 • Positive feedback loop PU.1-IL9 in Th9 promotes rheumatoid arthritis development., PMID:39164066 • The Role of Interleukin-9 in Cancer., PMID:31016637 • IL-9, a local growth factor for synovial T cells in inflammatory arthritis., PMID:26751012 • Locus of (IL-9) control: IL9 epigenetic regulation in cellular function and human disease., PMID:38825637 • Interleukin-9 and mast cells., PMID:23034251 • IL-9 sensitizes human TH2 cells to proinflammatory IL-18 signals in atopic dermatitis., PMID:39521283 • IL-9 and IL-9-producing cells in tumor immunity., PMID:32228589 • Interleukin-9 and T helper type 9 cells in rheumatic diseases., PMID:27159882 • IL-9-producing T cells: potential players in allergy and cancer., PMID:32788707
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.