- PackSize
- 50ug/100ug
- Target
- HSP90
- Reactivity
- Candida albicans
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Human
- Isotype
- scFv-heavy-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- HSP90
- Species
- --
- Gene ID-1
- P46598
- Uniprot
- --
- Background
- Efungumab is a monoclonal antibody with antifungal activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC).<br>• The HSP90 chaperone machinery., PMID:28429788<br/>• The HSP90 Family: Structure, Regulation, Function, and Implications in Health and Disease., PMID:30158430<br/>• Hsp90: structure and function., PMID:22955504<br/>• HSP90 multi-functionality in cancer., PMID:39148727<br/>• HSP90 and Noncoding RNAs., PMID:37638805<br/>• HSP90 mediates the connection of multiple programmed cell death in diseases., PMID:36335088<br/>• Cytosolic Hsp90 Isoform-Specific Functions and Clinical Significance., PMID:36139005<br/>• Hsp90: Bringing it all together., PMID:39889818<br/>• Organelle-specific Hsp90 inhibitors., PMID:26195286<br/>• Linking hsp90's role as an evolutionary capacitator to the development of cancer., PMID:34023771<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --