- PackSize
- 50ug/100ug
- Target
- Ganglioside GD3
- Reactivity
- General
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Chimeric
- Isotype
- IgG1-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- Ganglioside GD3
- Species
- --
- Gene ID-1
- PubChem CID: 20057323
- Uniprot
- --
- Background
- Mitumomab is an anti-idiotypic mouse IgG2b monoclonal antibody that mimics the ganglioside GD3. Mitumomab can be used for the research of small-cell lung carcinoma.<br>• GD3 ganglioside and apoptosis., PMID:12531552<br/>• Ganglioside GD3: structure, cellular distribution, and possible function., PMID:3903474<br/>• Ganglioside GD3 as a raft component in cell death regulation., PMID:21554197<br/>• A reappraisal of ganglioside GD3 expression in the CNS., PMID:8721669<br/>• Ganglioside GD3 regulates neural stem cell quiescence and controls postnatal neurogenesis., PMID:37667994<br/>• Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia., PMID:34133773<br/>• Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics., PMID:32743804<br/>• Possible regulation of ganglioside GD3 synthase gene expression with DNA methylation in human glioma cells., PMID:36897478<br/>• Ganglioside GD3 Regulates Inflammation and Epithelial-to-Mesenchymal Transition in Human Nasal Epithelial Cells., PMID:38612859<br/>• Development of Fluorescent Ganglioside GD3 and GQ1b Analogs for Elucidation of Raft-Associated Interactions., PMID:32951428<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --