- PackSize
- 50ug/100ug
- Target
- TGFB1/TGF-beta-1
- Reactivity
- Dog
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Caninized
- Isotype
- IgG2, kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- TGFB1/TGF-beta-1
- Species
- --
- Gene ID-1
- P54831
- Uniprot
- --
- Background
- Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris TGFB1 caninized monoclonal antibody. Cirevetmab is an immunomodulator.<br>• TGFB1 induces fetal reprogramming and enhances intestinal regeneration., PMID:37865088<br/>• Biomarkers for the identification of cardiac fibroblast and myofibroblast cells., PMID:29987445<br/>• Association between TGF-β gene polymorphism and myopia: A systematic review and meta-analysis., PMID:35905284<br/>• A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis., PMID:38980870<br/>• The effect of TGF-β<sub>1</sub> polymorphisms on pulmonary disease progression in patients with cystic fibrosis., PMID:35525938<br/>• Lack of association between the TGF-β(1) gene and development of COPD in Asians: a case-control study and meta-analysis., PMID:21556788<br/>• TGF-β and Diabetic Nephropathy: Lessons Learned Over the Past 20 Years., PMID:32039767<br/>• Direct effect of transforming growth factor-beta 1 (TGF-β1) on human apical papilla cell proliferation and mineralisation., PMID:34596309<br/>• Concentration change of TGF -β 1 in aqueous humor of rabbits., PMID:24507648<br/>• TGF-beta 1 codon 10 polymorphism is associated with cerebral SVD., PMID:22030425<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --