U-Blot® Research Grade Camoteskimab

Name: U-Blot® Research Grade Camoteskimab
SKU: WA2572
Availability: InStock

$9,999.00

Size:50ug

SKU: WA2572-50

Catalog No.: WA2572

Specification: 50ug/100ug

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product details Specifications Q & A Education

Product details, specifications, documents, and related products are available from the catalog record.

Product Overview

Catalog No.: WA2572
SKU: WA2572-50
Category: Biosimilar Antibodies
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: IFN-gamma-inducing factor
Reactivity: Human
Applications: ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host Species: Human
Isotype: IgG1-kappa
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 0.01M PBS, pH 7.4.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% purity as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Clonality: Monoclonal
Clone Number: --
Immunogen: Mammalian Cells
Alias: IFN-gamma-inducing factor, IL1F4, Interleukin-1 gamma, IL-18, IL-1 gamma, Interleukin-18, Interferon gamma-inducing factor, IGIF, IL18, Iboctadekin
Species: --
Gene ID-1: Q14116
Uniprot: --
Background: Camoteskimab (AVTX-007) is an anti-IL-18 monoclonal antibody with fully humanized, high-affinity. Camoteskimab is promising for research of cardiovascular diseases and autoinflammatory diseases, including adult-onset Still’s disease (AOSD) and multiple myeloma. • Mechanism and Regulation of NLRP3 Inflammasome Activation., PMID:27669650 • Inflammasomes in neuroinflammatory and neurodegenerative diseases., PMID:31015277 • IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells., PMID:31277710 • Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18., PMID:28954221 • NLRP3 Inflammasome and the IL-1 Pathway in Atherosclerosis., PMID:29880500 • Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases., PMID:31874111 • ACSL6-activated IL-18R1-NF-κB promotes IL-18-mediated tumor immune evasion and tumor progression., PMID:39292786 • Pretreatment with IL-15 and IL-18 rescues natural killer cells from granzyme B-mediated apoptosis after cryopreservation., PMID:38729924 • Interleukin-18 and COVID-19., PMID:34911594 • Short IL-18 generated by caspase-3 cleavage mobilizes NK cells to suppress tumor growth., PMID:39891018
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.