U-Blot® Research Grade Biciromab

U-Blot® Research Grade Biciromab
U-Blot® Research Grade Biciromab
$9,999.00
Size:50ug
SKU: WA2524-50

Catalog No.: WA2524

Specification: 50ug/100ug

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product details, specifications, documents, and related products are available from the catalog record.

Product Overview

Catalog No.
WA2524
SKU
WA2524-50
Category
Biosimilar Antibodies
Product Type
Other
Size
50ug/100ug
Stock Status
In stock
Available Stock
999
Minimum Order Quantity
1

Storage & Compliance

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Research Use Only
Yes

Additional Specifications

PackSize
50ug/100ug
Target
FGB
Reactivity
Human
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host Species
Mouse
Isotype
IgG1-kappa
Conjugate/Modification
--
Recommended Dilution Ratio
--
Composition
0.01M PBS, pH 7.4.
Purification Process
Protein A/G purified from cell culture supernatant.
Purity
>95% purity as determined by SDS-PAGE.
storageCondition
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Clonality
Monoclonal
Clone Number
--
Immunogen
Mammalian Cells
Alias
FGB, Fibrinogen beta chain
Species
--
Gene ID-1
P02675
Uniprot
--
Background
Indium (111In) biciromab (INN, trade name FibriScint, developed by Centocor) was a drug targeting fibrin, a protein involved in the clotting of blood. It was the Fab' fragment of a mouse monoclonal antibody labelled with the radioisotope indium-111 for the diagnosis of thromboembolism, but was withdrawn during clinical trials.<br>• A novel deletion in the fibrinogen beta chain (FGB) gene causing hypofibrinogenemia., PMID:31841708<br/>• A Novel Nonsense Mutation in <i>FGB</i> (c.1421G>A; p.Trp474Ter) in the Beta Chain of Fibrinogen Causing Hypofibrinogenemia with Bleeding Phenotype., PMID:33322159<br/>• Fibrinogen β chain and FXIII polymorphisms affect fibrin clot properties in acute pulmonary embolism., PMID:34783023<br/>• Genetic Variants in the <i>FGB</i> and <i>FGG</i> Genes Mapping in the Beta and Gamma Nodules of the Fibrinogen Molecule in Congenital Quantitative Fibrinogen Disorders Associated with a Thrombotic Phenotype., PMID:32610551<br/>• Fibrinogen beta chain may be a potential predict biomarker for pre-eclampsia: A preliminary study., PMID:36566955<br/>• Quantitative Proteomic Approach Targeted to Fibrinogen β Chain in Tissue Gastric Carcinoma., PMID:29518939<br/>• The β-Chain Mutation p.Arg17Stop Impairs Fibrinogen Synthesis and Secretion: A Nonsense Mutation Associated With Hypofibrinogenemia., PMID:39665495<br/>• Fibrinogen beta-chain -C148T polymorphism is associated with increased fibrinogen, C-reactive protein, and interleukin-6 in patients undergoing coronary artery bypass grafting., PMID:21499712<br/>• Investigating Association of rs5918 Human Platelets Antigen 1 and rs1800790 Fibrinogen β Chain as Critical Players with Recurrent Pregnancy Loss., PMID:30384452<br/>• [Relationship between fibrinogen B beta gene FGB -455G/A polymorphism and atherosclerotic cerebral infarction]., PMID:15300640<br/>
Tissue Expression
--
Signaling_pathway
--
Research Areas
--

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

WeChat / IMUcallm-Tech

HoursMonday-Friday 09:00-18:00 CST

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Keywords:Biosimilar Antibodies