- PackSize
- 50ug/100ug
- Target
- lukG
- Reactivity
- Staphylococcus aureus
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Human
- Isotype
- IgG1-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- lukG
- Species
- --
- Gene ID-1
- A0A6B5MC52
- Uniprot
- --
- Background
- Berlimatoxumab (ASN-2) is an antibody. Berlimatoxumab can be used for experiment research.<br>• Separately or combined, LukG/LukH is functionally unique compared to other staphylococcal bicomponent leukotoxins., PMID:24586678<br/>• Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity., PMID:31852826<br/>• Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies., PMID:27467113<br/>• Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH., PMID:25371205<br/>• Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories., PMID:35858453<br/>• Human antibody responses against non-covalently cell wall-bound Staphylococcus aureus proteins., PMID:29459694<br/>• Identification of a novel Staphylococcus aureus two-component leukotoxin using cell surface proteomics., PMID:20661294<br/>• Serum neutralizing antibody after rabies postexposure prophylaxis., PMID:945973<br/>• Pancreatic Enzyme Replacement Therapy Use in Infants With Cystic Fibrosis Diagnosed by Newborn Screening., PMID:29176494<br/>• Vitamin E regulates mitochondrial hydrogen peroxide generation., PMID:10490278<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --