- PackSize
- 50ug/100ug
- Target
- Ticagrelor
- Reactivity
- General
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Human
- Isotype
- Fab-G1-lambda
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- 274693-27-5
- Immunogen
- Mammalian Cells
- Alias
- Ticagrelor
- Species
- --
- Gene ID-1
- 274693-27-5
- Uniprot
- --
- Background
- Bentracimab (PB 2452) is a neutralizing monoclonal antibody that binds Ticagrelor and its major active circulating metabolite with high affinity. Bentracimab can rapidly reverse the antiplatelet effect of Ticagrelor.<br>• Ticagrelor., PMID:35396017<br/>• Ticagrelor with or without Aspirin in High-Risk Patients after PCI., PMID:31556978<br/>• Ticagrelor or Clopidogrel Monotherapy vs Dual Antiplatelet Therapy After Percutaneous Coronary Intervention: A Systematic Review and Patient-Level Meta-Analysis., PMID:38506796<br/>• Ticagrelor: clinical development and future potential., PMID:34258905<br/>• Ticagrelor resistance: a case series and algorithm for management of non-responders., PMID:34215660<br/>• Is ticagrelor worth its high cost and side-effects?, PMID:29730968<br/>• Ticagrelor in stable coronary disease., PMID:37586825<br/>• Ticagrelor-Associated Urticaria., PMID:35639409<br/>• Ticagrelor Use in Stroke Patients: Past, Present, and Future., PMID:34163168<br/>• Clopidogrel versus ticagrelor or prasugrel in patients aged 70 years or older with non-ST-elevation acute coronary syndrome (POPular AGE): the randomised, open-label, non-inferiority trial., PMID:32334703<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --