- PackSize
- 50ug/100ug
- Target
- HLA class II histocompatibility antigen
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Humanized
- Isotype
- IgG1-nd
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- HLA class II histocompatibility antigen, DRB1 beta chain, Human leukocyte antigen DRB1, HLA-DRB1
- Species
- --
- Gene ID-1
- P01911
- Uniprot
- --
- Background
- Apolizumab (Hu1D10) is a humanized monoclonal anti-Human leukocyte antigen-DR beta-chain antibody. Apolizumab can mediate apoptosis of chronic lymphocytic leukemia (CLL) cells in vitro.<br>• HLA common and well-documented alleles in China., PMID:30073798<br/>• Association of Human Leukocyte Antigen (HLA) class II (<i>DRB1</i> and <i>DQB1</i>) alleles and haplotypes with Rheumatoid Arthritis in Sudanese patients., PMID:37426636<br/>• Human-leukocyte antigen class II genes in early-onset obsessive-compulsive disorder., PMID:28562177<br/>• Association between human leukocyte antigen class II-DR-DQ and narcolepsy: a case control study., PMID:39150697<br/>• Human leukocyte antigen class II (DRB1 and DQB1) alleles and haplotypes frequencies in patients with pemphigus vulgaris among the Serbian population., PMID:27072514<br/>• Sarcoidosis and human leukocyte antigen class I and II genes: it takes two to tango?, PMID:15003948<br/>• Amino acid polymorphisms in human histocompatibility leukocyte antigen class II and proinsulin epitope have impacts on type 1 diabetes mellitus induced by immune-checkpoint inhibitors., PMID:37114039<br/>• A new strategy for systematically classifying HLA alleles into serological specificities., PMID:35538616<br/>• Diagnosis of sarcoidosis., PMID:18664976<br/>• Human leukocyte antigen class II alleles in Caucasian women with primary biliary cirrhosis., PMID:15713222<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --