- PackSize
- 50ug/100ug
- Target
- CD114
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Human
- Isotype
- IgG4-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- G-CSF receptor, CSF3R, GCSFR, G-CSF-R, CD114, Granulocyte colony-stimulating factor receptor
- Species
- --
- Gene ID-1
- Q99062
- Uniprot
- --
- Background
- Balugrastim (CG 10639) is a novel long-acting recombinant granulocyte colony-stimulating factor (G-CSF) obtained by means of a genetic fusion between recombinant human serum albumin and granulocyte colony-stimulating factor. Balugrastim can be used for the research of breast cancer.<br>• Characterization of G-CSF receptor expression in medulloblastoma., PMID:32642714<br/>• Gene Expression of <i>CSF3R</i>/CD114 Is Associated with Poorer Patient Survival in Glioma., PMID:38474265<br/>• CSF3R/CD114 mediates infection-dependent transition to severe asthma., PMID:30312710<br/>• Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus., PMID:29868014<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --