- PackSize
- 50ug/100ug
- Target
- FGF19
- Reactivity
- Human
- Applications
- ELISA, Functional assay, Research in vivo
- Host Species
- Mammalian Cells
- Isotype
- Recombinant human FGF19 analogs.
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Purified by Nickel column.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- --
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- FGF19, Fibroblast growth factor 19, FGF-19
- Species
- --
- Gene ID-1
- O95750
- Uniprot
- --
- Background
- Aldafermin (NGM282) is an analog of fibroblast growth factor 19. Aldafermin can be used for the research of nonalcoholic steatohepatitis (NASH).<br>• Modulation of metabolic syndrome by fibroblast growth factor 19 (FGF19)?, PMID:15140837<br/>• FGF19-Induced Inflammatory CAF Promoted Neutrophil Extracellular Trap Formation in the Liver Metastasis of Colorectal Cancer., PMID:37345586<br/>• The FGF family: biology, pathophysiology and therapy., PMID:19247306<br/>• Mechanisms of Parenteral Nutrition-Associated Liver and Gut Injury., PMID:31872510<br/>• Metabolic Messengers: fibroblast growth factor 15/19., PMID:32694803<br/>• FGF19/FGFR4-mediated elevation of ETV4 facilitates hepatocellular carcinoma metastasis by upregulating PD-L1 and CCL2., PMID:36907560<br/>• Effect of Fibroblast Growth Factor (FGF) 19 and 21 on Hip Geometry and Strength in Post-menopausal Osteoporosis (PMO)., PMID:39341924<br/>• Fibroblast growth factor 15/19 expression, regulation, and function: An overview., PMID:35301051<br/>• Effect of Bariatric Surgery on Metabolic Diseases and Underlying Mechanisms., PMID:34827579<br/>• Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice., PMID:28650457<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --