- PackSize
- 50ug/100ug
- Target
- IFNAR1/IFNAR2
- Reactivity
- Human
- Applications
- ELISA, Functional assay, Research in vivo
- Host Species
- Human
- Isotype
- Fusion - ALB (albumin, human serum albumin, HSA) 25-609 - IFNA2 (interferon alpha 2) *b (R46, H57) 24-188
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Purified by ion exchange chromatography.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- --
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- IFNAR1/IFNAR2
- Species
- --
- Gene ID-1
- P17181, P48551
- Uniprot
- --
- Background
- Albinterferon alfa-2B (alb-IFN) is a recombinant protein consisting of interferon alfa-2b genetically fused to human albumin. Albinterferon alfa-2B can be used for the research of chronic hepatitis C.<br>• The Role of Structure in the Biology of Interferon Signaling., PMID:33281831<br/>• Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFNτ directs normal uterine fate for bovine early implantation., PMID:35907379<br/>• Proximal protein landscapes of the type I interferon signaling cascade reveal negative regulation by PJA2., PMID:38802340<br/>• IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections., PMID:30473701<br/>• Construction of an IFNAR1 knockout MDBK cell line using CRISPR/Cas9 and its effect on bovine virus replication., PMID:39100665<br/>• Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling., PMID:36118237<br/>• Structure-function of type I and III interferons., PMID:38608537<br/>• Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury., PMID:24480543<br/>• Mechanism of Rhinovirus Immunity and Asthma., PMID:34691038<br/>• Structural basis for the recognition of IFNAR1 by the humanized therapeutic monoclonal antibody QX006N for the treatment of systemic lupus erythematosus., PMID:38649079<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --