Product information
Background:ribosomal protein S6 kinase B1(RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013],
Product Overview
- Catalog No.
- WR4035
- SKU
- WR4035-50
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- Aurora A
- Reactivity
- Human,
- Applications
- WB,IHC,IF,IP,ELISA
- MW(Calculated)
- 45kD
- MW(Observed)
- 45kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate
- Unmodified
- Modification
- --
- Recommended Dilution Ratio
- IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
- Composition
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification Process
- Protein A
- Purity
- --
- Storage Condition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone Number
- PT0150R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- AURKA AIK AIRK1 ARK1 AURA AYK1 BTAK IAK1 STK15 STK6
- Protein Name
- Aurora A
- Alias
- Aurora kinase A;Aurora 2;Aurora/IPL1-related kinase 1;ARK-1;Aurora-related kinase 1;hARK1;Breast tumor-amplified kinase;Serine/threonine-protein kinase 15;Serine/threonine-protein kinase 6;Serine/threonine-protein kinase aurora-A;
- Organism-1
- Human
- Gene ID-1
- 6790
- SwissProt-1
- O14965
- Organism-2
- Mouse
- Gene ID-2
- 20878
- SwissProt-2
- P97477
- Organism-3
- Rat
- Gene ID-3
- --
- SwissProt-3
- P59241
- Organism-4
- --
- Gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Membranous
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)