Product information
Background:Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008],
Product Overview
- Catalog No.
- WR4048
- SKU
- WR4048-50
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- ACE2
- Reactivity
- Human,
- Applications
- WB,IHC,IF,IP,ELISA
- MW(Calculated)
- 130kD
- MW(Observed)
- 130kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate
- Unmodified
- Modification
- --
- Recommended Dilution Ratio
- IHC 1:1000-1:4000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
- Composition
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification Process
- Protein A
- Purity
- --
- Storage Condition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone Number
- PT0172R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- ACE2 UNQ868/PRO1885
- Protein Name
- ACE2
- Alias
- Angiotensin-converting enzyme 2;ACE-related carboxypeptidase;Angiotensin-converting enzyme homolog;ACEH;Metalloprotease MPROT15;[Cleaved into: Processed angiotensin-converting enzyme 2]
- Organism-1
- Human
- Gene ID-1
- 59272
- SwissProt-1
- Q9BYF1
- Organism-2
- Mouse
- Gene ID-2
- 70008
- SwissProt-2
- Q8R0I0
- Organism-3
- Rat
- Gene ID-3
- 302668
- SwissProt-3
- Q5EGZ1
- Organism-4
- --
- Gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Membrane
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)