Sku: C4621
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$999.00
Size:1/pk,100/Cs
SKU: C4530
Catalog No.: 2228766
Specification: 1/pk,100/Cs
Stock: In stock
Product details, specifications, documents, and related products are available from the catalog record. Learn more
Product information
2.2 Genome & Classification
The S. suis genome is a circular chromosome of approximately 2.0–2.1 Mb. Through multilocus sequence typing (MLST), over 4,200 sequence types (STs) have been identified to date, reflecting the extremely high genetic variability of this bacterium, which complicates the development of broadly protective vaccines. S. suis produces over 70 virulence factors, several of which have been extensively studied as potential vaccine targets.
| 6 | 7 | 7 |
| 6 | 6 | 6 | 7 |
| 66 | 76 |
3. Related Products & Services
- l Recombinant Antigens & Receptors
- l Antibodies
- l Detection Kits
- l Recombinant Protein Expression Services
- l Antibody Development Services
4. Resources
5. References
- Brangsch, H., Berens, C., Fuchs, S., et al. (2026). Genome characteristics and type IV effector protein repertoire of Coxiella burnetii depend rather on Genomic Groups than on host species. BMC microbiology, 26(1), 393.
- Yuan, J., Zhang, Y., Song, L., et al. (2025). Modulation of host cell pathways by Coxiella burnetii Dot/Icm effectors. mLife, 4(6), 579–598.
- Bird, L. E., Xu, B., Hobbs, A. D., et al. (2025). Coxiella burnetii manipulates the lysosomal protease cathepsin B to facilitate intracellular success. Nature communications, 16(1), 3844.
- Arunima, A., Niyakan, S., Butler, S. M., et al. (2025). CYP1B1-AS1 regulates CYP1B1 to promote Coxiella burnetii pathogenesis by inhibiting ROS and host cell death. Nature communications, 16(1), 7493.
- Palanisamy, R., Zhang, Y., Zhang, G. (2024). Role of Type 4B Secretion System Protein, IcmE, in the Pathogenesis of Coxiella burnetii. Pathogens (Basel, Switzerland), 13(5), 405.
2.3 What Are S. suis Virulence Factors？
The virulence factors of S. suis primarily include:
| 2 | 34 | 4 | 4 | |
| 88 | 77 | 66 | 56 |
2.3.1 Dynamic Regulation of Capsular Polysaccharide (CPS)
Product Overview
- Catalog No.
- 2228766
- SKU
- C4530
- Category
- Antibody
- Product Type
- Other
- Size
- 1/pk,100/Cs
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Research Use Only
- Yes
Tech Support
ucallm
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Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
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Contact Support
Emailinfo@mail.ucallm.com
Phone+(1)-866-986-9598
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Product Q&A
Technical answers curated for this product by Ucallm support.
General33
2.2 Genome & Classification
The S. suis genome is a circular chromosome of approximately 2.0–2.1 Mb. Through multilocus sequence typing (MLST), over 4,200 sequence types (STs) have been identified to date, reflecting the extremely high genetic variability of this bacterium, which complicates the development of broadly protective vaccines. S. suis produces over 70 virulence factors, several of which have been extensively studied as potential vaccine targets.
2.3 What Are S. suis Virulence Factors？
The virulence factors of S. suis primarily include:
Virulence Factor | Main Function |
Capsular polysaccharide (CPS) | The most important virulence factor; evades phagocytosis by masking immunogenic surface components; CPS expression is dynamically regulated |
Suilysin (SLY) | Secreted cholesterol-dependent cytotoxin; facilitates bacterial invasion, dissemination, and blood-brain barrier disruption |
Extracellular protein factor (EF) | Immunomodulatory protein involved in immune evasion |
Two-component system Ihk/Irr | Regulates anti-phagocytic capacity and virulence; inhibits macrophage actin polymerization via the PepO axis |
PepO (aminopeptidase) | Activates p38 and ERK1/2 pathways via TLR2, inhibiting actin polymerization and phagocytosis |
ShgH | Dual histidine/glutamine transporter; involved in nutrient acquisition, anti-phagocytosis, and biofilm modulation |
Glycosyl hydrolase GhA | Promotes bacterial adhesion, blood survival, and anti-phagocytic capacity |
STK (Ser/Thr kinase) | Regulates acid resistance and virulence via phosphorylation of FadR |
2.3.1 Dynamic Regulation of Capsular Polysaccharide (CPS)
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