11.10测试

11.10测试
11.10测试
$55.00
SKU: ddf3455

Stock: Sold out

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. The differentiation of CFU-E (Colony Forming Unit-Erythroid) cells into erythrocytes can only be accomplished in the presence of EPO. Physiological levels of EPO in adult mammals are maintained primarily by the kidneys, whereas levels in fetal or neonatal mammals are maintained by the liver.

Kit Name

Cat.No.

Size

UcallM® FECTMAX mRNA Transfection Reagent

E1092

100 μL

 

Product Overview

Catalog No.
ddf3455
SKU
ddf3455
Category
CATtest
Product Type
Other
Stock Status
Sold out
Available Stock
0
Minimum Order Quantity
1

Biological Attributes

Research Area
研究领域测试, testresearch area

Storage & Compliance

Research Use Only
Yes

Documents & Compliance

SDS
SDS
COA
COA
SDS / MSDS
MSDS
Datasheet
Datasheet

Tech Support

ucallm

01

Documents

DatasheetDatasheetCOACOASDSSDSDocumentSDS
02

Research Areas

Research Area研究领域测试Research Areatestresearch area
03

Related Resources

other资源测试资源测试
04

Topics

Topic Pluripotent Stem Cell-Derived Vascular Endothelial Lineage
05

Related Services

Service10.19测试测试
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

WeChat / IMUcallm-Tech

HoursMonday-Friday 09:00-18:00 CST

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Product Q&A

Technical answers curated for this product by Ucallm support.

Generalww

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General33

2.2 Genome & Classification

The S. suis genome is a circular chromosome of approximately 2.0–2.1 Mb. Through multilocus sequence typing (MLST), over 4,200 sequence types (STs) have been identified to date, reflecting the extremely high genetic variability of this bacterium, which complicates the development of broadly protective vaccines. S. suis produces over 70 virulence factors, several of which have been extensively studied as potential vaccine targets.

2.3 What Are S. suis Virulence Factors？

The virulence factors of S. suis primarily include:

Virulence Factor

Main Function

Capsular polysaccharide (CPS)

The most important virulence factor; evades phagocytosis by masking immunogenic surface components; CPS expression is dynamically regulated

Suilysin (SLY)

Secreted cholesterol-dependent cytotoxin; facilitates bacterial invasion, dissemination, and blood-brain barrier disruption

Extracellular protein factor (EF)

Immunomodulatory protein involved in immune evasion

Two-component system Ihk/Irr

Regulates anti-phagocytic capacity and virulence; inhibits macrophage actin polymerization via the PepO axis

PepO (aminopeptidase)

Activates p38 and ERK1/2 pathways via TLR2, inhibiting actin polymerization and phagocytosis

ShgH

Dual histidine/glutamine transporter; involved in nutrient acquisition, anti-phagocytosis, and biofilm modulation

Glycosyl hydrolase GhA

Promotes bacterial adhesion, blood survival, and anti-phagocytic capacity

STK (Ser/Thr kinase)

Regulates acid resistance and virulence via phosphorylation of FadR

2.3.1 Dynamic Regulation of Capsular Polysaccharide (CPS)

GeneralQA1

QA223

Keywords:CATtest研究领域测试testresearch area