Overview
Protein acetylation is a common post-translational modification (PTM) characterized by the addition of acetyl groups to lysine residues or protein N-termini. Regulated by acetyltransferases and deacetylases, acetylation plays important roles in chromatin remodeling, gene expression, protein function regulation, and cellular metabolism. Dysregulated acetylation is associated with various diseases, making acetylation analysis valuable for understanding disease mechanisms and identifying potential therapeutic targets.
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